AB0383 OCULAR MANIFESTATIONS DURING GIANT CELL ARTERITIS

Background: Horton’s disease (HD) or giant cell arteritis (GCA) is a segmental and plurifocal inflammatory panarteritis, predominant in large medium sized vessels. Ocular damage during frequent considered the most serious damage, possibly causing blindness 15% of cases recent series (1). Objectives: Describe different ophthalmological manifestations GCA. Methods: This retrospective monocentric descriptive study 19 files subjects diagnosed with HD, hospitalized internal medicine department de Sousse between January 2000 December 2020. Results: The average age patients at diagnosis was 70 years, extremes 53 92 years. There were 14 females (71.4%) 5 males (28.6%). Ophthalmologic present 13 (71%), 6 whom female. Decreased visual acuity reported 8 (58.33%) biolateral one case, blur 9 (75%), eye pain two cases. Ophthalmological examination normal (42%). A decrease objective 4 (21%). One case nodular episcleritis noted. fundus showed anterior ischemic optic neuropathy 2 (10.5%) left atrophy another case. field performed showing associated retrobulbar neuritis. Therapeutically, Methylprednisolone boli prescribed neuropathy, followed by oral corticosteroid therapy dose 1mg/kg/day. 0.7 mg/kg/day prednisone other Blindness irreversible. Conclusion: common diseases HD are acute neuritis, retinal artery occlusion posterior neuropathy. Episcleritis rare ophthalmologic manifestation this vasculitis (2). More exceptionally, may cause NORB affecting vessels that supply nerve (< 5% cases)(3,4). In our studies, neuritis less observed than literature. probably due to reduced number patients. References: [1]M.Khedher. I.Rachdi. Z.Aydi. F.Daoud. B.Ben Dhaou. F.Boussema. Eye disease: about 42 La Revue Médecine Interne 2017; 38:115. [2]Rim Klii. Wafa Chebbi. Nodular episcleritis: an unusual inaugural disease. Pan Afr Med J 2015; 21: 20. [3]M.EssouriI.RachdiF.DaoudZ.AydiH.ZoubeidiB.Ben Dhaou et al. Retrobulbar Optic Neuropathy Internal Medicine. 2018; 39: 132. [4]M González-Gay, C García-Porrúa, Llorca, H Hajeer, F Brañas, Dababneh Visual arteritis. Trends clinical spectrum 161 Medicine (Baltimore) 2000;79(5):283-92. Disclosure Interests: None declared